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The program is covering medications only for people who meet the definition of obesity, not for those who are overweight, Moore said
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Yet, although these studies focused on the nuclear and metabolic roles of MOTS-c, it can be inferred that MOTS-c polymorphisms can have a functional impact, including metabolism and adaptive responses

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Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore
