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FDA has officially approved Merck's Lipfendra (enlicitide), marking a historic milestone as the first-ever once daily oral PCSK9 inhibitor to lower LDL-C ("bad" cholesterol) in adults with hypercholesterolemia and heterozygous familial hypercholesterolemia (HeFH)

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[38] found that semaglutide increased the risk of gastrointestinal side effects (RR 1.49, 95% CI 1.381.60)

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