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Side Effects and Tolerability: All three drugs have similar side effect profiles , since they all work on the incretin system
One of the most well-known studies is the STEP (Semaglutide Treatment Effect in People with Obesity) clinical trial
There's also a larger question hanging over the Medicare breakthrough: Unless the Trump administration extends or replaces the demonstration program, obesity drug coverage is scheduled to expire at the end of 2027
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But a quick improvement in blood sugar levels can temporarily worsen diabetic retinopathy