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More than 90% of the study population received neither form of treatment during the study period (while 9.2% received GLP-1 RAs and 0.4% received surgery)

1,961 participants with BMI of 30+ (or 27+ with at least one weight-related condition) received either semaglutide 2.4 mg or placebo weekly for 68 weeks, alongside lifestyle intervention

It effectively evades DPP-IV inactivation by substituting alanine with glycine in the 8th position

Effect of Pre-meal Water Consumption on Energy Intake and Satiety in Non-obese Young Adults

Researchers continue to investigate its molecular characteristics, receptor interactions and biochemical behaviour using controlled laboratory techniques