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Tirzepatide gave you a window of reduced appetite and improved metabolic function

high GLP-1 = good. Its going to get a little complicated here, so put on your thinking cap

On vascular and capillary walls, GLP-1 activation leads to cAMP activation, which then increases protein kinase A activity

At the time of study start (July 2023), the only available RCT evidence demonstrated a reduction in alcohol intake in response to GLP-1RAs only in people with obesity, so we focused our study on that population 19

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