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REFERENCES 1.Sung H, Siegel RL, Torre LA, et al

The success of brands such as Wegovy and Zepbound has spurred demand beyond diabetic populations, positioning GLP-1 therapies as central to chronic weight management protocols

In 2023, the FDA required the manufacturers of Ozempic and Wegovy to update the drugs warning label to include the risk of bowel obstruction, a severe gastrointestinal side effect

Semaglutide can restore the decreased gut microbiota diversity in db/db mice and reverse the changes in specific bacterial levels induced by a high-fat diet (HFD) (Somm et al., 2021)

Understanding how hormonal integration shapes behavioral output is particularly important in addiction medicine, where metabolic state, reward drive, and affective regulation are tightly interwoven