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In addition, -glucan can increase the number of beneficial bacteria such as Bifidobacterium and Lactobacillus , playing an important role in maintaining the balance of the gut microbiome [67]

Early research suggests it may offer complementary metabolic benefits, different tissue distribution and action compared to GLP-1, potentially unique effects on energy metabolism, and possible applications beyond traditional GLP-1 uses

Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation

ELIXA trial included patients with recent cardiovascular event (patients with acute coronary syndrome 180 days before randomization), and although there was no benefit in MACE reduction in lixisenatide treated patients compared to placebo, results revealed cardiovascular safety of lixisenatide in this specific high risk population (38, 40)

ColonBroom started as a high-fiber gut health supplement , earning attention for its role in supporting digestion and regularity