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The first STEP trial (a series of large clinical trials that investigated who semaglutide helps and in what context) reported a 14.9% reduction in body weight over 72 weeks for participants taking 2.4 mg weekly

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Clinical Category Guidance & Safety Mandates Thyroid History Warning Strictly contraindicated if you or any family members have a history of Medullary Thyroid Carcinoma (MTC) or Multiple Endocrine Menasia syndrome type 2 (MEN 2)

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