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Accordingly, models in animals lacking DPP-4 underline the importance of this factor in the regulation of glucose metabolism: in fact, DPP-4-deficient rats showed better glucose tolerance and higher insulin and GLP-1 levels than controls [51]

[DOI] [PubMed] [Google Scholar] [190].O'Reilly MW, Kempegowda P, Jenkinson C, Taylor AE, Quanson JL, Storbeck KH, et al
10.1016/j.pneurobio.2010.07.003 158

Most GLP-1 users are taking the medication for weight or metabolic management

Journal of diabetes research, 2018, 1205121
