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GLP-1-derived peptides regulate rat and human TRPV1 activation independently of GLP-1R expression To verify the potential involvement of GLP-1R in the observed inhibitory effects on TRPV1 channels, we transiently transfected rat TRPV1 into HEK293T cells

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[1] [2] Administered as a once-weekly subcutaneous injection, Ozempic works by enhancing insulin secretion in response to elevated blood glucose, suppressing glucagon release, and slowing gastric emptying

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