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Dulaglutide, a newer once-weekly GLP-1 receptor agonist, significantly increased heart rate (2.8 bpm, 95% CI: 1.5-4.2) compared with placebo at the dose of 1.5 mg [95]

GLP-1RAs may also delay gastric emptying, potentially leading to retained gastric contents and aspiration risk

[DOI] [PMC free article] [PubMed] [Google Scholar] 95.Anton S.D., Moehl K., Donahoo W.T., et al

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These systems often use biocompatible polymers like polyvinylpyrrolidone (PVP), polyvinyl alcohol (PVA), sodium alginate, or gelatin, and may include functional components such as egg-derived proteins or silk fibroin to mimic biological properties and enhance mechanical strength and drug stability [40]