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doi: 10.1053/j.gastro.2011.02.018 [DOI] [PMC free article] [PubMed] [Google Scholar] 63

Pharmacologic approaches to glycemic treatment of type 2 diabetes: synopsis of the 2020 American Diabetes Associations Standards of Medical Care in Diabetes Clinical Guideline

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To further investigate why these three missense mutations led to a significantly increased GLP-1R ECD affinity of semaglutide mutant 524, a comprehensive structural biophysical analysis [50] was conducted for the 10000 structural models built by Modeller [44] with a structural electrostatic perspective

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