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So, for women who are following Hormone Replacement Therapy (HRT) by taking a pill, the decreased absorption of the drugs can actually cause a sudden (but unwanted) drop in estrogen causing mood swings and hot flashes to unexpectedly return

Appetite suppression with retatrutide is typically most effective at higher maintenance doses, so hunger is often more noticeable during the early titration phase

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2024 doi: 10.1124/pharmrev.123.001045
Last updated:22-05-2025 Around 64% of the adult UK population suffers from obesity, making weight management solutions highly sought after
