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Within the SGLT2i cohort, 47% received empagliflozin, 27% received dapagliflozin and 25% received canagliflozin
A new preclinical study at Northwestern Universitys Feinberg School of Medicine found that disrupting complex I function in mouse dopaminergic neurons led to progressive PD-related motor deficits, with loss of dopamine release in the substantia nigra being critical for motor deficits (40)
You might explore a microdosing regimen if: Youre new to GLP-1 therapy and worried about side effects You previously experienced unpleasant reactions at full doses You have health conditions that affect how you metabolize medication Youre seeking a customized approach to fit dietary, activity or financial constraints Explore potential benefits Though research on GLP-1 microdosing is still emerging, anecdotal reports and early studies suggest several advantages that may make this strategy worth considering
Hitting a plateauwhile taking a GLP-1, or notis a normal physiological response, not proof the treatment stopped working, Shapiro stresses
Some types of GLP-1 medications Many GLP-1 medications are available in injectable form
