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This metabolic shift is beneficial long-term but can initially trigger fatigue as your cells adjust to improved glucose handling

This is relevant for the short-acting GLP-1 agonists, whereas tachyphylaxis rapidly develops for the long-acting agonists [8]
Many healthcare providers recommend pausing or reassessing GLP-1 medications during an active diverticulitis flare

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doi: 10.2337/diabetes.47.7.1046
