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Description
The decrease in systolic blood pressure is aseparate entity of GLp-1 effect unrelated to weight loss [1]

The distinction between evidence-based pharmaceutical GLP-1 medications and unregulated patch products is critical for patient safety and treatment efficacy

Most people do not see immediate blood pressure changes

While compounded medications are not FDA-approved (only brand-name Ozempic and Wegovy carry FDA approval), 503A compounders are federally regulated, and their products undergo rigorous testing

Zepbound (tirzepatide for obesity) launched November 2023 and went into shortage within weeks due to overwhelming demand
