glp-1 vs metformin Comparison of type 2 diabetes medications: GLP-1RA, SGLT2i, and GLP-1 Analogs and DeFronzo's Octet

Targets Ther

It should also be noted that an oral form of semaglutide was developed by adding an agent to the drug formulation, which increases intestinal permeability, sodium N-(8-(2-hydroxybenzoyl)amino)caprylate (SNAC), but the lower bioavailability of the molecule requires daily administration to achieve glycemic control equivalent to that obtained by the form administered subcutaneously

This represents a more than threefold higher risk of stomach paralysis for those on injectable GLP-1 medications

Both cause slurred speech, poor coordination, confusion, and drowsiness

Obesity should be treated like a chronic disease, and patients must continue the medication long-term to sustain the results achieved from the medication