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More and more people realize that obesity is a chronic degenerative disease

Expect that familiar pattern of increased nausea for a few days after the first injection at the new dose, then improvement over the following weeks

Thieu VT, Robinson S, KennedyMartin T, Boye KS, GarciaPerez LE
doi: 10.1002/1097-0142(19810501)47:9 3.0.CO;2-6 9 WiviottSDRazIBonacaMPMosenzonOKatoETCahnAet al

The addition of energy expenditure enhancement via glucagon agonism addresses a limitation inherent to GLP-1-only approaches, which reduce energy intake but do not meaningfully increase energy output
