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Finally, the brain receptors controlling hunger and satiety are responsive to GLP-1

Accordingly, understanding the physiological and behavioral effects of cannabis use, recreationally or medicinally, is of paramount importance

Recent structural studies reveal that ligand-specific conformations of class B GPCRs modulate -arrestin recruitment, receptor trafficking, and signaling duration, thereby influencing both therapeutic outcomes and side effect profiles [27]

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E.MartchenkoA.CoxB
