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HS is increasingly recognized as a disease driven by systemic inflammation and metabolic dysfunction, with evidence supporting the use of treatments that address both pathways

The GLP-1 consumer over-indexes on food and beverage at about 9% higher than the non-user. Circana data shows 5.3% of consumers are actively embracing GLP-1s, and the number may rise to double-digits for those who have at least tried the drug, according to Lyons Wyatt

Novo Nordisk in particular just could not keep up with demand

Although preliminary studies across various metabolic and mental disorders flank these promising findings regarding potential treatments of motivational dysfunction, we also highlight the need to investigate reward phases beyond anticipation to fully capitalize on the potential of gut-based interventions, specifically for mental disorders

In a T-cell-driven adoptive transfer (AdTr) colitis mouse model, liraglutide significantly improved disease activity markers, including histological activity in colonic tissue and the colon weight-to-length ratio, likely due to its ability to reduce CCL20, IL-33, and IL-22 [23]