glp-1 gip dual agonist GIPR/GLP-1R therapies for diabetes and weight loss—chemistry, physiology, and clinical applications glp 1 and gip glp

Description

Highlights Sodium-glucose cotransporter-2 inhibitors (SGLT2-i) and glucagon-like peptide-1 receptor agonists (GLP-1RA) provide modest but clinically meaningful blood pressure (BP) lowering effects in people with hypertension and cardiometabolic comorbidities

Sleep: The Free Longevity Drug A nationwide analysis in SLEEP Advances found that insufficient sleep ranked just behind smoking as a predictor of shortened life expectancy across over 3,000 US counties (McAuliffe et al., 2025)

Semaglutide GLP-1 is a prescription medication that needs to be prescribed to you for obesity, and it is typically available through pharmacies with a valid prescription from a healthcare provider like us at Abundant Life Healthcare

Since then, several GLP-1s for obesity have been approved for new indications such as secondary cardiovascular risk reduction (Wegovy), sleep apnea (Zepbound) and metabolic dysfunction-associated steatohepatitis or MASH (Wegovy)