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In addition to LCFAs, 2-monoacylglycerol, the other component of triglycerides, can also induce GLP-1 release via G protein-coupled receptor 119 113,114,115
Common examples include semaglutide (Ozempic, Wegovy, Rybelsus), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda)
Peptide YY regulates bone turnover in rodents
The risk of worsening heart failure events alone dropped by 46% (HR 0.54)
Youre going from a dual-receptor medication to a single-receptor one, and for many patients, that difference is noticeable
