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The same is true for any medication that causes significant weight loss

The medication acts on appetite and satiety through gut-hormone pathways rather than treating one area of the body

Depending on the decision of the safety group to proceed to a higher dose level, it was planned to escalate to 40 mg from week 5 (in the 40 and 60 mg cohorts), and to 60 mg from week 7 (in the 60 mg cohort)

Many patients find their appetite naturally drops, which makes a balanced diet easier to sustain

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