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Cagrilintide is a newer long-acting amylin analogue

Emerging evidence has demonstrated that co-administration of glucose-dependent insulinotropic peptide (GIP) and GLP-1 results in enhanced insulinotropic effect in an additive way with significant glucagonostatic response, compared with the administration of each hormone separately

[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Tuesta L.M., Chen Z., Duncan A., Fowler C.D., Ishikawa M., Lee B.R., Liu X.-A., Lu Q., Cameron M., Hayes M.R., et al

This signals a significant escalation in the FDAs oversight of the rapidly expanding weight-loss drug market and marks a second wave of enforcement following the Agencys broader crackdown on pharmaceutical direct-to-consumer (DTC) advertising