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Waters bridging interactions with ligand are shown as ball-and-stick model
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La precocidad de la separacin de las curvas de aparicin de MACE entre los brazos de SEMA y placebo23 sugiere una potencial participacin directa de SEMA en los resultados del estudio SELECT, a travs de efectos promotores de angiognesis y reduccin de estrs oxidativo e inflamacin, en el contexto de acciones antiaterognicas derivadas de la activacin del GLP-1R que favorecen la funcin endotelial y la supervivencia celular7 (fig
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