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79 Notably, a high percentage of striatal DAT (at least 47%) needs to be occupied by cocaine in addicts before they report subjective effects of the drug, 80 implying that modulating DAT surface expression alters the reinforcing effects of cocaine in humans

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Women also show higher prevalence rates at 38 per 100,000 compared to men at 9.6 per 100,000 [4]

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