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2 Note: New patients are classified based on prior prescription activity

The global prevalence of CKD is approximately 10% and is increasing, driven by rising rates of type 2 diabetes (T2D) and obesity [1, 4]

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These data also support the conclusion that Fab 3F52 directly blocked binding of BMS21, implying that Fab 3F52 occupies partially the orthosteric binding site of the GLP-1R TM domain, which is interesting considering the spatial relationship of the ECD, the antibody and the TM domain

NeurologyLive Mantovani, Alessandro et al