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Description
& Blundell, T

An interesting pattern from clinical data: 12% of participants continued losing weight through week 48 without ever hitting a plateau

Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea

It is possible that an analogous compensation occurs in models with constitutive deficiency of GLP1 receptors, which prevents the identification of GLP1 receptors as required in the regulation of energy balance at basal levels

But the receptor-based mechanism does not work that way
