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Zepbound (tirzepatide) targets weight loss through GLP-1 and GIP receptors, but emerging research suggests potential mood and anxiety benefits beyond the scale

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Clinical Significance: The 2025 updates reaffirm that while HbA1c remains central, a one-number-fits-all strategy is outdated

Both tirzepatide and semaglutide cause nausea and appetite suppression, but tirzepatide's dual-receptor action produces different tolerability patterns