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Blood sugar In type 2 diabetes research, changes in HbA1c were observed in a dose-dependent way

Animals were given ad libitum access to food for the entirety of the study except on day 14 mice were fasted for 6 h prior to ipPTT

10.1056/NEJMoa1305889 125

Nutritional deficiency, the underrecognized risk The most clinically significant long-term consequence of GLP-1 therapy isn't a drug side effect, it's the nutritional consequence of eating significantly less food for months or years

In addition, tirzepatide, even at the lowest maintenance dose of 5 mg, can reduce body weight to a greater extent compared with GLP-1 RAs including subcutaneous semaglutide which, in turn, has been shown to be superior to other glucose-lowering agents [28]