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Description
By improving systemic insulin sensitivity, semaglutide also attenuates adipose tissue lipolysis, thereby lowering the circulation of free fatty acids (FFAs) that would otherwise be delivered to the liver for TG synthesis [16]
Molecular Metabolism 39101008
Duration of Use : Semaglutide is approved for long-term use
Recent research data has shown that the expression of lipid metabolism genes adiponectin (APN), Adipo R, AMPK, PPAR mRNA and protein is significantly increased after 48 hours of treatment with different concentrations of GLP-1 compared with the model group of adipose hepatocytes [108]
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