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Description
FDA-approved GLP-1 receptor agonists include semaglutide (Ozempic, Wegovy, Rybelsus), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), lixisenatide (Adlyxin), exenatide (Bydureon BCise), and tirzepatide (Mounjaro, Zepbound)though tirzepatide is technically a dual GIP/GLP-1 receptor agonist
The inner mitochondrial membrane of BAT contains a high density of uncoupling protein 1 (UCP1), which translocates protons to the mitochondrial matrix, uncoupling substrate oxidation from ATP production and generating heat
Most importantly, they all suffered from a cardiovascular disease or were indicated as high risk for the occurrence of cardiovascular events
Retrieved January 15, 2026, from Tempia Valenta S, Nicastri A, Perazza F, Marcolini F, Beghelli V, Atti AR, Petroni ML
