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Clinical Evidence : Multiple meta-analyses show a small but statistically significant reduction in body weight (approximately 1.1 to 2.0 lbs), waist circumference, and body fat percentage compared to placebo

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Lowering the risk of type 2 diabetes, hypertension, and cardiovascular conditions

This gradual increase helps the body adapt to the medication and improves weight loss outcomes

In some cases, temporary dose reduction or pausing dose escalation of the GLP-1 medication may be appropriate while nutritional status is optimized, though this decision should be made collaboratively between patient and provider