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Hydration is also critical
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When to Adjust Your Dose or Switch Formulations Dose escalation should follow a structured protocol: most tirzepatide regimens begin at 2.5 mg weekly and increase by 2.5 mg every 4 weeks until reaching an effective dose or tolerability limit
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Side effects like nausea, vomiting, or diarrhea can cause dehydration, while significant appetite suppression can lead to low iron or protein levels if not managed properly
