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Looking ahead, we are excited to begin our Phase 1 study for RT-114, Ranis GLP-1/GLP-2 dual agonist in partnership with ProGen this year. The nonclinical PK and PD study was conducted to examine the effects of semaglutide delivered orally via the RaniPill (RT-116) versus a SC injection comparator group

4 mg/3 ml, waarbij 1 mg per injectie wordt toegediend

[DOI] [PubMed] [Google Scholar] 53.Lau D, Padwal R
For the main background medication subgroup analyses, the trial product estimand was used to reflect the effect of oral semaglutide versus each comparator without the confounding effect of rescue medication