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Efficacy of liraglutide for weight loss among patients with type 2 diabetes: the SCALE Diabetes randomized clinical trial

Research indicates that the body's homeostatic mechanisms actively defend against sustained weight loss through increased hunger signaling and reduced satiety hormone production

H., Eiden, L

Figure 1 2 MASLDs pathophysiology and current treatment MASLD is characterized by an abnormal accumulation of lipids in hepatocytes, commonly occurring in the context of obesity, insulin resistance, and T2DM-key features of metabolic syndrome that substantially affect patient quality of life and long-term prognosis ( The complex pathophysiology of MASLD calls for integrated, multi-faceted therapeutic regimens and improved diagnostic tools to enhance clinical outcomes

Adequate protein intake and resistance exercise during treatment are important countermeasures