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The result for many patients is a meaningful reduction in cravings, a quieter relationship with food, and less of that constant mental noise around eating

For estimation for this estimand, the intercurrent events and resulting missing values were handled by a hybrid approach using retrieved dropouts imputation from the same treatment group or using all nonmissing data assuming missing at random

The weight loss effect is believed to result from a combination of reduced calorie intake, increased energy expenditure, and potential changes in fat metabolism

The gradual escalation gives your body time to adjust and reduces gastrointestinal side effects that are most common during dose changes

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