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doi: 10.1111/dom.13053

Second-generation: cilofexor (GS-9674), tropifexor (LJN452) Cilofexor is a potent, selective, nonsteroidal agonist of FXR that predominantly activates intestinal FXR without involvement of the enterohepatic circulation

The effect of glucagon-like peptide I (GLP-I) on glucose elimination in healthy subjects depends on the pancreatic glucoregulatory hormones

Others are located in the dorsal raphe nucleus, which produces nearly all of the serotonin used by the forebrainthe same neurotransmitter system targeted by selective serotonin reuptake inhibitors

Jardiance belongs to the SGLT2 inhibitor family, a class approved primarily for type 2 diabetes management