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The GLP-1 hormone plays a key role in coordinating digestion with metabolism, helping the body interpret incoming nutrients and respond appropriately

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One-third of the patients lost at least 10 kg

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The researchers found that for the treatment regimen estimand, the mean change from baseline in hemoglobin A1c concentration was 1.69, 1.86, and 1.94 percent with 4, 9, and 12 mg of retatrutide, respectively, versus 0.81 percent with placebo, resulting in estimated treatment differences of 0.88, 1.04, and 1.12 percent, respectively, versus placebo