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10.1186/s13195-024-01666-7 30 DaiC.HangY.ShostakA.PoffenbergerG.HartN.PrasadN.et al (2017)

But retatrutide can also cause a temporary increase in heart rate that needs to be carefully monitored, since it can lead to more serious complications, such as heart arrhythmia, says Dr

GLP-1 medications are typically initiated at low doses and increased slowly over several weeks or months, as per the product SmPC (Summary of Product Characteristics)
GLP-1 medications are safe, FDA-approved treatments that have been extensively studied in clinical trials
Post-Treatment Effects Gastrointestinal discomfort or changes in bowel habits may persist for a short period following discontinuation