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Contraindications Tolcapone is contraindicated in: Active liver disease Elevated baseline liver enzymes History of tolcapone-induced hepatotoxicity Severe hepatic impairment Hypersensitivity To view or add a comment, sign in Excellent graphic overview on pharmacological and clinical aspects of oral semaglutide in T2DM by Ney Carter Borges MD M.Sc

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Int J Obes (Lond) 2024;48(8):11181125

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The turnabout for each came after both insurers ended automatic coverage of the blockbuster GLP-1 weight loss drugs such as Wegovy and Zepbound solely for the treatment of obesity