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70 16% of the baseline level), and (4) diuretic and natriuretic responses to intravenous infusion of GLP-1 were blunted (urine flow 53.4 4.3 vs

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On average, volunteers in the retatrutide clinical trial who received the study drug rather than a placebo lost an average of 70.3 pounds over about a year-and-a-half, with more than 45% of participants losing more than 30% of their body weight

2026;3:101465 DOI: Received: January 25, 2026 Accepted: March 26, 2026 Published: April 02, 2026 Academic Editor: Marijn Speeckaert, Universitair Ziekenhuis Ghent, Belgium Epiploic appendagitis is a rare, self-limiting inflammatory condition of the colonic epiploic appendages