glp 1 7 36 amide GLP-1(7-36), acetate (Glucagon-like peptide-1 (GLP-1)(7-36), amide acetate) | Insulinotropic Peptide GLP-1 & GLP-2
Description
[DOI] [PubMed] [Google Scholar] 29.Ganakumar V., Fernandez C.J., Pappachan J.M

2021;171 doi: 10.1016/j.phrs.2021.105782

Results Compared with GLP-1 receptor agonists, the SGLT-2 inhibitor-GLP-1 receptor agonist combination was associated with a 30% lower risk of major adverse cardiovascular events (7.0 v 10.3 events per 1000 person years

Recommended protocol: Washout: 30 to 35 days (conservative, recommended) Starting dose: 2mg weekly (resist the urge to start higher) Week 5: escalate to 4mg Week 9: escalate to 8mg Week 13: escalate to 12mg Yes, you start at 2mg despite coming from 15mg tirzepatide

The bitter taste receptor activation pathway requires relatively small amounts of the triggering compound because the receptors are highly sensitive
