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Description
New real-world data from Israel (n=6356, Lancet: eClinicalMedicine 2025) offers the first direct comparison between GLP-1 receptor agonists and bariatric metabolic surgery (BMS) in reducing the risk of obesity-related cancers (ORCs)
The effects of DHEA and DHEAS were time- and dose-dependent, with half maximal effective concentration (EC 50 ) in the low nanomolar range
Gene therapy and other advanced approaches remain earlier in development but represent potential long-term solutions for obesity treatment
From utilization to mortality assumptions, these medications raise new cost and risk considerations for actuaries and insurers
wrote the first draft of the manuscript
