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Drugs used to treat conditions such as chronic inflammation may have undesirable side effects, while nutraceuticals such as melatonin are known to be beneficial in treating inflammation due to their high safety and tolerability 2

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UnitedHealthcare Medicare Advantage Zepbound coverage as of May 2026: Standard obesity indication: generally excluded under Medicare Part D weight-loss drug rules OSA indication (after December 2024): coverage path with sleep-medicine documentation 2025 IRA $2,000 annual out-of-pocket cap applies to covered Part D drugs Members seeking Zepbound coverage through UnitedHealthcare Medicare Advantage should pursue the OSA indication when applicable, as obesity-only requests typically face exclusion