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Scientists from the WHO recently wrote: "The approval of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for the treatment of obesity creates potential for a transformation of the whole health system that could halt and reverse the global obesity pandemic through prevention and effective integrated management." Growing crisis South Africa is grappling with dual diabetes and obesity epidemics, on top of the HIV and TB epidemics, but is not responding effectively, resulting in high obesity and diabetes-related deaths

In its Complete Response Letter, FDA said results from the Phase III ROMAN trial, in combination with the GT-201 trial, were not sufficiently persuasive to establish substantial evidence of avasopasems effectiveness and safety in reducing these mouth sores
