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The incidence is dose-dependent, meaning higher doses produce more nausea

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Cholecystokinin-from local gut hormone to ubiquitous messenger
However, side effects such as gastrointestinal discomfort and mild hypoglycemia were common, and all GLP-1 are categorized as pregnancy Category C by the U.S
The abnormal signal pathways will lead to excessive production of FFAs and ROS in adipocytes and hepatocytes, which is a milestone of the first step to develop MASH (Portincasa et al., 2024)
