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Complementary in vitro studies revealed that liraglutide exerted a dose-dependent inhibitory effect on the secretion of pro-inflammatory mediators, including interleukin 6 (IL-6), prostaglandin E2 (PGE2), and nitric oxide (NO), and suppressed the expression of inflammatory genes in chondrocytes and macrophages [45]

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Sukumaran and colleagues treated Zucker lean and obese rates with either vehicle or the GLP-1 agonist liraglutide (LIRA) for 8 weeks [66]

D.MerglerS.SchulzA.et al (2018)

The majority of these studies focus on alcohol consumption, but there are also studies for opioids and nicotine being initiated