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Some patients remain at 8mg if side effects at 12mg prove uncomfortable

Systemic allergic reactions , whilst less common, may manifest as: Widespread urticaria (hives) raised, itchy welts that can appear anywhere on the body Generalised pruritus (itching) without visible rash Maculopapular rash flat red areas with small raised bumps Angioedema deeper swelling, particularly around the face, lips, or throat It is important to distinguish between common injection site reactions and genuine allergic responses

Redondo MJ, Hagopian WA, Oram R, et al

ATGL, the rate limiting enzyme for lipolysis, is required for these effects

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