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retatrutide phase 2 obesity trial Retatrutide, a TRIPLE agonist (GLP1, GIP, glucagon), just released results demonstrating 25% weight loss in half of people with #obesity. This amount of weight loss has not been accomplished Perceived benefits of treatment for
Description
This article reviews the mode of action for DPP-4 inhibitors and their application in the treatment of T2D

In HFD-caused hyperlipidemic rats, oat beta-glucan lowered body weight gain inhibits hepatic adipocyte hyperplasia, and decrease epididymal fat pad
Diabetes 1 June 2021
In the SGLT2i group, 101 participants were hospitalised (mean number of hospitalisations=2.7, median number of hospitalisations=2), with a mean and median length of stay of 2.4 and 2 days, respectively

While partly attributable to weight loss, the magnitude suggests additional direct vascular effects
